Tag: Borderline

  • The Psycho-Epigenetics of Pace of Life Syndrome: How Life Events Shape Identity, Personality, and the Biology of Mortality

    The Psycho-Epigenetics of Pace of Life Syndrome: How Life Events Shape Identity, Personality, and the Biology of Mortality

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    Epigenetics is the study of how outside influences can change the way our genes work without changing our DNA itself. It looks at how things in our environment—like what we eat, how much stress we feel, our daily habits, and our life experiences—can turn genes on or off. These changes can affect how our cells work and how we develop, and they can sometimes be passed on to future generations. Among the most profound reorientations in contemporary psychological and biological science is the recognition that human identity, personality, and health outcomes are not fixed properties of genetic inheritance alone — they are dynamic, experience-dependent, and continuously rewritten by the events, environments, and relationships that constitute a human life.

    The emerging field of psycho-epigenetics—the study of how our psychological experiences can cause lasting changes in how our genes are expressed, without changing the DNA sequence itself—now shows, at the level of our cells, how this process works (Cowell, 2019 ). When this framework is combined with the evolutionary model called the Pace-of-Life Syndrome (PoLS)—which suggests that organisms adjust their whole biological and behavioural profile in response to early-life conditions of adversity and unpredictability—it offers a clear and clinically important explanation of how lived experience shapes who we become(Réale et al., 2018), in our very bodies …


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    References

    Cobre, B. et al. (2025) Molecular Insights into Trauma: A Framework of Epigenetic Pathways to Resilience Through Intervention. Available at: https://bradleycobre.org/wp-content/uploads/2025/07/Molecular-insights-into-trauma_A-framework-of-epigenetic-pathways-to-resilience-through-intervention.pdf (Accessed: 25 July 2026).

    Cowell, W.J. (2019) ‘Epigenetic Modifications in Stress Response Genes Associated With Childhood Trauma’, Frontiers in Psychiatry, 10, 808. Available at: https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2019.00808/full (Accessed: 25 July 2026).

    Epel, E.S., Blackburn, E.H., Lin, J., Dhabhar, F.S., Adler, N.E., Morrow, J.D. and Cawthon, R.M. (2004) ‘Accelerated telomere shortening in response to life stress’, Proceedings of the National Academy of Sciences, 101(49). Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC534658/ (Accessed: 25 July 2026).

    Frontiers in Psychology (2025) ‘Psychological and behavioural responses to death anxiety in older adults with chronic illnesses: a systematic integrative review’, Frontiers in Psychology, 16, 1684385. Available at: https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2025.1684385/full (Accessed: 25 July 2026).

    GeroScience (2025) ‘Epigenetic age acceleration and mortality risk prediction in US adults’, GeroScience. Springer Nature. Available at: https://link.springer.com/article/10.1007/s11357-025-01604-x (Accessed: 25 July 2026).

    Glick, D. et al. (2025) ‘From trauma to resilience: psychological and epigenetic adaptations in the third generation of Holocaust survivors’, Scientific Reports, 15. Available at: https://www.nature.com/articles/s41598-025-12085-5 (Accessed: 25 July 2026).

    Kaminsky, Z. et al. (2024) ‘On the role of epigenetic modifications of HPA axis in posttraumatic stress disorder and resilience’, Journal of Neurophysiology, 131(5). Available at: https://journals.physiology.org/doi/full/10.1152/jn.00345.2024 (Accessed: 25 July 2026).

    Lindqvist, D., Epel, E.S., Mellon, S.H., Penninx, B.W., Révész, D., Verhoeven, J.E., Reus, V.I., Lin, J., Mahan, L., Hough, C.M., Rosser, R., Wolkowitz, O.M. (2015) ‘Childhood Adversities Are Associated with Shorter Telomere Length at Adult Age both in Individuals with an Anxiety Disorder and Controls’, PLOS ONE. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC2876034/ (Accessed: 25 July 2026).

    Međedović, J. (2023) ‘Pace-of-Life Syndrome (POLS)’, in Shackelford, T.K. (ed.) Encyclopedia of Sexual Psychology and Behavior. Cham: Springer. Available at: https://link.springer.com/rwe/10.1007/978-3-031-08956-5_1677-1 (Accessed: 25 July 2026).

    Otto, B., Kokkelink, L. and Brüne, M. (2021) ‘Borderline Personality Disorder in a “Life History Theory” Perspective: Evidence for a Fast “Pace-of-Life-Syndrome”‘, Frontiers in Psychology, 12, 715153. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350476/ (Accessed: 25 July 2026).

    Perroud, N. et al. (2018) ‘Epigenetics in Personality Disorders: Today’s Insights’, Frontiers in Psychiatry. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC6252387/ (Accessed: 25 July 2026).

    Qiu, J. and Xu, X. (2025) ‘On the effectiveness of Buddhist view of life and death in regulating mortality salience’, Frontiers in Psychology, 15, 1523125. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11751067/ (Accessed: 25 July 2026).

    Réale, D., Garant, D., Humphries, M.M., Bergeron, P., Careau, V. and Montiglio, P.O. (2010) ‘Personality and the emergence of the pace-of-life syndrome concept at the population level’, Philosophical Transactions of the Royal Society B: Biological Sciences, 365(1560), pp. 4051–4063. Available at: https://royalsocietypublishing.org/doi/abs/10.1098/rstb.2010.0208 (Accessed: 25 July 2026).

    Réale, D., Montiglio, P.O., Dingemanse, N.J. and Moiron, M. (2018) ‘Pace-of-life syndromes: a framework for the adaptive integration of behaviour, physiology and life history’, Behavioral Ecology and Sociobiology, 72, 116. Available at: https://link.springer.com/article/10.1007/s00265-018-2473-y (Accessed: 25 July 2026).

    Seattle Anxiety Specialists (2023) How Mortality Changes Our Behaviors: Insights from Death Anxiety Research. Available at: https://seattleanxiety.com/psychiatrist/2023/7/10/how-mortality-changes-our-behaviors-insights-from-death-anxiety-research (Accessed: 25 July 2026).

  • Petulant Borderline Personality Disorder (BPD)

    Petulant Borderline Personality Disorder (BPD)

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    Petulant BPD can be characterised by a pattern of defiance, stubbornness, and irritability. People with this subtype of BPD may struggle with feelings of perceived injustice and often have difficulty regulating their emotions. They may exhibit behaviours such as sulking, pouting, or throwing temper tantrums when they do not get their way.

    These behaviours can be challenging for both the individual with BPD and those around them. The constant push and pull of emotions can make it difficult to maintain relationships, leading to feelings of isolation and loneliness. It can also be exhausting for loved ones to constantly navigate the ups and downs of the individual with petulant BPD.

    However, it is important to remember that petulant BPD is a symptom of a larger mental health condition and should be treated with compassion and understanding. Therapy, medication, and support from loved ones can all help individuals with BPD learn to manage their symptoms and improve their overall quality of life.

    If you or someone you know is struggling with petulant BPD, know that there is help available. Seeking therapy from a mental health professional who specialises in BPD can provide valuable tools and techniques for managing symptoms. Additionally, joining a support group or connecting with others who have BPD can offer a sense of community and understanding.

    Living with petulant BPD may be challenging, but with the right support and treatment, it is possible to lead a fulfilling and meaningful life. Remember, you are not alone, and there is always hope for a brighter future.

  • Understanding the Four Subtypes of Borderline Personality Disorder (BPD)

    Understanding the Four Subtypes of Borderline Personality Disorder (BPD)

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    There are four subtypes of BPD that are commonly recognised within the mental health community: the impulsive subtype, the petulant subtype, the self-destructive subtype, and the internalising subtype.

    The impulsive subtype of BPD is characterised by impulsivity and a tendency to act without thinking of the consequences. Individuals with this subtype may engage in reckless behaviours such as substance abuse, reckless driving, or risky sexual behaviour. They may also struggle with anger management issues and have difficulty controlling their impulses.

    The petulant subtype of BPD is marked by a pattern of stubbornness, defiance, and oppositional behaviour. These individuals may have a strong fear of abandonment and may become angry or resentful when they feel like they are being ignored or rejected. They may also have difficulty expressing their emotions in a healthy way and may resort to passive-aggressive behavior to communicate their feelings.

    The self-destructive subtype of BPD is characterised by self-harming behaviours such as cutting, burning, or hitting oneself. Individuals with this subtype may also struggle with feelings of emptiness and worthlessness, which can lead to suicidal ideation. They may engage in self-destructive behaviours as a way to cope with their emotional pain and may have difficulty forming and maintaining healthy relationships.

    The internalising subtype of BPD is marked by a pattern of self-blame, shame, and guilt. Individuals with this subtype may have a strong fear of abandonment and may be highly sensitive to criticism or rejection. They may struggle with feelings of inadequacy and may have difficulty asserting their needs and boundaries in relationships.

    While these subtypes can help mental health professionals better understand the ways in which BPD may manifest in different individuals, it’s important to remember that BPD is a complex and multifaceted disorder. Treatment for BPD typically involves a combination of therapy, medication, and support from loved ones. By working with a mental health professional who understands the nuances of the disorder, individuals with BPD can learn to manage their symptoms and lead fulfilling lives.

  • Can a Person With Borderline Personality Disorder (BPD) Be a Good Friend?

    Can a Person With Borderline Personality Disorder (BPD) Be a Good Friend?

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    Given these symptoms, it can be challenging for individuals with BPD to maintain healthy relationships, including friendships. However, that does not mean that a person with BPD cannot be a good friend. In fact, with the right and understanding, individuals with BPD can form meaningful and supportive friendships.

    One of the key in being a good friend is communication. People with BPD may have difficulty expressing their emotions and thoughts in a clear and coherent manner. This can sometimes lead to misunderstandings and conflicts in relationships. However, with self-awareness and therapy, individuals with BPD can learn to communicate effectively and express their needs and boundaries to their friends.

    Another important aspect of being a good friend is empathy and understanding. Friends of individuals with BPD may need to be patient and empathetic towards their struggles and challenges. It is essential for both parties to have open and honest conversations about the disorder and how it may impact their friendship.

    People with BPD may also benefit from setting boundaries and practising self-care in their friendships. It is important for individuals with BPD to recognise when they are feeling overwhelmed or triggered and to communicate this to their friends. By taking care of their own needs and boundaries, individuals with BPD can maintain healthier and more fulfilling friendships.

    In conclusion, while it may be challenging for individuals with BPD to navigate friendships, it is certainly possible for them to be good friends. With self-awareness, therapy, and support from understanding friends, individuals with BPD can form meaningful and supportive relationships. It is essential for both parties to practise empathy, communication, and self-care in order to create strong and lasting friendships.

  • The Development of Borderline Personality Disorder in Childhood

    The Development of Borderline Personality Disorder in Childhood

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    One of the key factors associated with the development of BPD in childhood is early trauma or adverse childhood experiences (ACEs). Children who experience abuse, neglect, or other forms of trauma are at a higher risk for developing BPD later in life. These traumatic experiences can disrupt the child’s sense of safety and security, leading to difficulties regulating emotions and forming healthy relationships. Additionally, genetic factors and neurobiological differences may also contribute to the development of BPD in childhood.

    Symptoms of BPD in childhood can be similar to those seen in adults, but may manifest in different ways. Children with BPD may exhibit extreme emotional instability, intense mood swings, and difficulty managing anger. They may also struggle with impulsivity, self-harm, and suicidal thoughts or behaviours. These symptoms can interfere with a child’s daily functioning and relationships, making it essential for parents, teachers, and mental health professionals to recognise and address these issues early on.

    Early intervention is key in managing and treating BPD in childhood. Therapy, such as dialectical behaviour therapy (DBT) or play therapy, can help children learn coping skills, emotional regulation, and healthy relationship-building strategies. It is also important for parents and caregivers to provide a stable and supportive environment for the child, promoting a sense of safety and security.

    As with any mental health condition, early identification and intervention are crucial in managing BPD in childhood. By understanding the potential risk factors and symptoms of BPD in children, we can work towards providing the necessary support and resources to help these individuals lead healthy and fulfilling lives. Remember, it is never too early to seek help for a child struggling with mental health issues.

  • Lost in Reality: Understanding Dissociation

    Lost in Reality: Understanding Dissociation

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    There are different forms of dissociation, ranging from mild to severe. Some people may experience it as a fleeting moment of being lost in thought or daydreaming, while others may have more severe episodes where they lose track of time, have gaps in memory, or feel like they are watching themselves from a distance. In extreme cases, dissociation can lead to the development of dissociative disorders such as Dissociative Identity Disorder (formerly known as Multiple Personality Disorder ).

    It’s important to understand that dissociation is not a sign of weakness or a lack of control. It is a natural response to trauma or overwhelming stress, and for some people, it can be a helpful coping mechanism. However, frequent or severe dissociation can have a significant impact on a person’s mental health and well-being. It can interfere with daily functioning, relationships, and overall quality of life.

    If you or someone you know is experiencing dissociation, it’s important to seek help from a mental health professional. Therapy, medication, and other forms of treatment can help manage dissociative symptoms and address any underlying trauma or stress that may be contributing to them. It’s also important to practise self-care and relaxation techniques to help reduce stress and prevent dissociative episodes.

    It’s time to break the stigma surrounding dissociation and increase awareness and understanding of this common experience. By educating ourselves and others about dissociation, we can create a more compassionate and supportive environment for those who are struggling with this complex phenomenon. Remember, you are not alone, and there is help available. Let’s work together to navigate the challenging terrain of dissociation and find a path towards healing and recovery.

  • Evolutionary Perspectives on Borderline Personality Disorder

    Evolutionary Perspectives on Borderline Personality Disorder

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    One evolutionary theory suggests that the traits associated with BPD may have once served a survival function in our ancestors. For example, traits such as impulsivity and emotional reactivity may have helped our ancestors respond quickly to threats in their environment. In modern society, however, these same traits can lead to dysfunctional behaviours and difficulties in relationships.

    Another evolutionary perspective on BPD focuses on attachment theory. According to this theory, individuals with BPD may have experienced early childhood traumas or disruptions in their attachment relationships, leading to difficulties in forming and maintaining healthy relationships later in life. From an evolutionary standpoint, strong attachment bonds were essential for survival in our ancestors, as they provided protection and support.

    One of the key features of BPD is emotional dysregulation, which may stem from a heightened sensitivity to social cues and threats in the environment. This hypersensitivity may have once been adaptive, helping our ancestors navigate complex social dynamics and avoid potential dangers. However, in modern society, this same sensitivity can lead to difficulties in regulating emotions and forming stable relationships.

    It is important to note that evolutionary perspectives on BPD are still in the early stages of research, and more studies are needed to further explore these theories. Additionally, while evolutionary perspectives can provide valuable insights into the development of BPD, they do not negate the importance of psychological and environmental factors in understanding this complex disorder.

    Overall, understanding the evolutionary origins of BPD can help us gain a deeper insight into the underlying mechanisms of the disorder and inform more effective treatment strategies. By taking a holistic approach to understanding BPD, we can better support individuals struggling with this condition and improve their quality of life.